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The Use of Hyaluronic Acid after Tendon Surgery and in Tendinopathies

Viscosupplementation with hyaluronic acid is safe and effective in the management of osteoarthritis, but its use in the treatment of tendon disorders has received less attention. The aim of this review is to summarize the current knowledge on this topic, evaluating experimental and clinical trials....

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Autores principales: Abate, Michele, Schiavone, Cosima, Salini, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033484/
https://www.ncbi.nlm.nih.gov/pubmed/24895610
http://dx.doi.org/10.1155/2014/783632
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author Abate, Michele
Schiavone, Cosima
Salini, Vincenzo
author_facet Abate, Michele
Schiavone, Cosima
Salini, Vincenzo
author_sort Abate, Michele
collection PubMed
description Viscosupplementation with hyaluronic acid is safe and effective in the management of osteoarthritis, but its use in the treatment of tendon disorders has received less attention. The aim of this review is to summarize the current knowledge on this topic, evaluating experimental and clinical trials. A search of English-language articles was performed using the key search terms “hyaluronic acid” or “viscosupplementation” combined with “tendon,” “tendinopathy,“ “adhesions,“ or “gliding,“ independently. In quite all the experimental studies, performed after surgical procedures for tendon injuries or in the treatment of chronic tendinopathies, using different hyaluronic acid compounds, positive results (reduced formation of scars and granulation tissue after tendon repair, less adhesions and gliding resistance, and improved tissue healing) were observed. In a limited number of cases, hyaluronic acid has been employed in clinical practice. After flexor tendon surgery, a greater total active motion and fingers function, with an earlier return to work and daily activities, were observed. Similarly, in patients suffering from elbow, patellar, and shoulder tendons disorders, pain was reduced, and function improved. The positive effect of hyaluronic acid can be attributed to the anti-inflammatory activity, enhanced cell proliferation, and collagen deposition, besides the lubricating action on the sliding surface of the tendon.
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spelling pubmed-40334842014-06-03 The Use of Hyaluronic Acid after Tendon Surgery and in Tendinopathies Abate, Michele Schiavone, Cosima Salini, Vincenzo Biomed Res Int Review Article Viscosupplementation with hyaluronic acid is safe and effective in the management of osteoarthritis, but its use in the treatment of tendon disorders has received less attention. The aim of this review is to summarize the current knowledge on this topic, evaluating experimental and clinical trials. A search of English-language articles was performed using the key search terms “hyaluronic acid” or “viscosupplementation” combined with “tendon,” “tendinopathy,“ “adhesions,“ or “gliding,“ independently. In quite all the experimental studies, performed after surgical procedures for tendon injuries or in the treatment of chronic tendinopathies, using different hyaluronic acid compounds, positive results (reduced formation of scars and granulation tissue after tendon repair, less adhesions and gliding resistance, and improved tissue healing) were observed. In a limited number of cases, hyaluronic acid has been employed in clinical practice. After flexor tendon surgery, a greater total active motion and fingers function, with an earlier return to work and daily activities, were observed. Similarly, in patients suffering from elbow, patellar, and shoulder tendons disorders, pain was reduced, and function improved. The positive effect of hyaluronic acid can be attributed to the anti-inflammatory activity, enhanced cell proliferation, and collagen deposition, besides the lubricating action on the sliding surface of the tendon. Hindawi Publishing Corporation 2014 2014-05-08 /pmc/articles/PMC4033484/ /pubmed/24895610 http://dx.doi.org/10.1155/2014/783632 Text en Copyright © 2014 Michele Abate et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Abate, Michele
Schiavone, Cosima
Salini, Vincenzo
The Use of Hyaluronic Acid after Tendon Surgery and in Tendinopathies
title The Use of Hyaluronic Acid after Tendon Surgery and in Tendinopathies
title_full The Use of Hyaluronic Acid after Tendon Surgery and in Tendinopathies
title_fullStr The Use of Hyaluronic Acid after Tendon Surgery and in Tendinopathies
title_full_unstemmed The Use of Hyaluronic Acid after Tendon Surgery and in Tendinopathies
title_short The Use of Hyaluronic Acid after Tendon Surgery and in Tendinopathies
title_sort use of hyaluronic acid after tendon surgery and in tendinopathies
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033484/
https://www.ncbi.nlm.nih.gov/pubmed/24895610
http://dx.doi.org/10.1155/2014/783632
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