JTT-130, a Novel Intestine-Specific Inhibitor of Microsomal Triglyceride Transfer Protein, Improves Hyperglycemia and Dyslipidemia Independent of Suppression of Food Intake in Diabetic Rats

We investigated the effects of JTT-130 on glucose and lipid metabolism independent of the suppression of feeding by comparing with pair-fed animals. Male Zucker diabetic fatty (ZDF) rats were divided into control, JTT-130 treatment, and pair-fed groups. The rats were fed with a regular powdered diet...

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Detalles Bibliográficos
Autores principales: Sakata, Shohei, Ito, Makoto, Mera, Yasuko, Sasase, Tomohiko, Yamamoto, Hiromi, Kakutani, Makoto, Ohta, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033514/
https://www.ncbi.nlm.nih.gov/pubmed/24895641
http://dx.doi.org/10.1155/2014/803832

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