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A new molecular explanation for age-related neurodegeneration: The Tyr682 residue of amyloid precursor protein
Emerging evidence supports the role for the intracellular domains of amyloid precursor protein (APP) in the physiology and function of APP. In this short report, I discuss the hypothesis that mutation of Tyr682 on the Y(682)ENPTY(687) C-terminal motif of APP may be directly or indirectly associated...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BlackWell Publishing Ltd
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033529/ https://www.ncbi.nlm.nih.gov/pubmed/23943322 http://dx.doi.org/10.1002/bies.201300041 |