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Quality by design approach for viral clearance by protein a chromatography

Protein A chromatography is widely used as a capture step in monoclonal antibody (mAb) purification processes. Antibodies and Fc fusion proteins can be efficiently purified from the majority of other complex components in harvested cell culture fluid (HCCF). Protein A chromatography is also capable...

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Detalles Bibliográficos
Autores principales:	Zhang, Min, Miesegaes, George R, Lee, Michael, Coleman, Daniel, Yang, Bin, Trexler-Schmidt, Melody, Norling, Lenore, Lester, Philip, Brorson, Kurt A, Chen, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033531/ https://www.ncbi.nlm.nih.gov/pubmed/23860745 http://dx.doi.org/10.1002/bit.24999

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