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Site-targeted non-viral gene delivery by direct DNA injection into the pancreatic parenchyma and subsequent in vivo electroporation in mice

The pancreas is considered an important gene therapy target because the organ is the site of several high burden diseases, including diabetes mellitus, cystic fibrosis, and pancreatic cancer. We aimed to develop an efficient in vivo gene delivery system using non-viral DNA. Direct intra-parenchymal...

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Detalles Bibliográficos
Autores principales:	Sato, Masahiro, Inada, Emi, Saitoh, Issei, Ohtsuka, Masato, Nakamura, Shingo, Sakurai, Takayuki, Watanabe, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033566/ https://www.ncbi.nlm.nih.gov/pubmed/23946268 http://dx.doi.org/10.1002/biot.201300169

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