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Standardization of RNA Chemical Mapping Experiments

[Image: see text] Chemical mapping experiments offer powerful information about RNA structure but currently involve ad hoc assumptions in data processing. We show that simple dilutions, referencing standards (GAGUA hairpins), and HiTRACE/MAPseeker analysis allow rigorous overmodification correction,...

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Detalles Bibliográficos
Autores principales:	Kladwang, Wipapat, Mann, Thomas H., Becka, Alex, Tian, Siqi, Kim, Hanjoo, Yoon, Sungroh, Das, Rhiju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033625/ https://www.ncbi.nlm.nih.gov/pubmed/24766159 http://dx.doi.org/10.1021/bi5003426

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