Dual C–H Functionalization of N-Aryl Amines: Synthesis of Polycyclic Amines via an Oxidative Povarov Approach

[Image: see text] Iminium ions generated in situ via copper(I) bromide catalyzed oxidation of N-aryl amines readily undergo [4 + 2] cycloadditions with a range of dienophiles. This method involves the functionalization of both a C(sp(3))–H and a C(sp(2))–H bond and enables the rapid construction of...

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Detalles Bibliográficos
Autores principales: Min, Chang, Sanchawala, Abbas, Seidel, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033637/
https://www.ncbi.nlm.nih.gov/pubmed/24786302
http://dx.doi.org/10.1021/ol501073f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033637/
https://www.ncbi.nlm.nih.gov/pubmed/24786302
http://dx.doi.org/10.1021/ol501073f

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