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Applying Label-Free Quantitation to Top Down Proteomics

[Image: see text] With the prospect of resolving whole protein molecules into their myriad proteoforms on a proteomic scale, the question of their quantitative analysis in discovery mode comes to the fore. Here, we demonstrate a robust pipeline for the identification and stringent scoring of abundan...

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Detalles Bibliográficos
Autores principales: Ntai, Ioanna, Kim, Kyunggon, Fellers, Ryan T., Skinner, Owen S., Smith, Archer D., Early, Bryan P., Savaryn, John P., LeDuc, Richard D., Thomas, Paul M., Kelleher, Neil L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033644/
https://www.ncbi.nlm.nih.gov/pubmed/24807621
http://dx.doi.org/10.1021/ac500395k