Cargando…
Applying Label-Free Quantitation to Top Down Proteomics
[Image: see text] With the prospect of resolving whole protein molecules into their myriad proteoforms on a proteomic scale, the question of their quantitative analysis in discovery mode comes to the fore. Here, we demonstrate a robust pipeline for the identification and stringent scoring of abundan...
Autores principales: | Ntai, Ioanna, Kim, Kyunggon, Fellers, Ryan T., Skinner, Owen S., Smith, Archer D., Early, Bryan P., Savaryn, John P., LeDuc, Richard D., Thomas, Paul M., Kelleher, Neil L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033644/ https://www.ncbi.nlm.nih.gov/pubmed/24807621 http://dx.doi.org/10.1021/ac500395k |
Ejemplares similares
-
The C-Score: A Bayesian
Framework to Sharply
Improve Proteoform Scoring in High-Throughput Top Down Proteomics
por: LeDuc, Richard D., et al.
Publicado: (2014) -
Integrated Bottom-Up and Top-Down Proteomics of Patient-Derived Breast Tumor Xenografts
por: Ntai, Ioanna, et al.
Publicado: (2016) -
The emergence of top-down proteomics in clinical research
por: Savaryn, John P, et al.
Publicado: (2013) -
An informatic framework for decoding protein complexes by top-down mass spectrometry
por: Skinner, Owen S., et al.
Publicado: (2016) -
Mapping Intact Protein Isoforms in Discovery Mode Using Top Down Proteomics
por: Tran, John C., et al.
Publicado: (2011)