Cu-Catalyzed Direct Amidation of Aromatic C–H Bonds: An Access to Arylamines

[Image: see text] A Cu-catalyzed aromatic C–H amidation with phthalimide under oxygen as a terminal oxidant without using additional additives has been achieved. This reaction has the broad substrate scope and shows moderate to good yields in most cases. This method is complementary to the previousl...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Hui, Qiao, Xixue, Yang, Shiping, Shen, Zengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033662/
https://www.ncbi.nlm.nih.gov/pubmed/24735227
http://dx.doi.org/10.1021/jo5003592
_version_ 1782317859802710016
author Xu, Hui
Qiao, Xixue
Yang, Shiping
Shen, Zengming
author_facet Xu, Hui
Qiao, Xixue
Yang, Shiping
Shen, Zengming
author_sort Xu, Hui
collection PubMed
description [Image: see text] A Cu-catalyzed aromatic C–H amidation with phthalimide under oxygen as a terminal oxidant without using additional additives has been achieved. This reaction has the broad substrate scope and shows moderate to good yields in most cases. This method is complementary to the previously reported metal-catalyzed C–H amination systems.
format Online
Article
Text
id pubmed-4033662
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-40336622015-04-15 Cu-Catalyzed Direct Amidation of Aromatic C–H Bonds: An Access to Arylamines Xu, Hui Qiao, Xixue Yang, Shiping Shen, Zengming J Org Chem [Image: see text] A Cu-catalyzed aromatic C–H amidation with phthalimide under oxygen as a terminal oxidant without using additional additives has been achieved. This reaction has the broad substrate scope and shows moderate to good yields in most cases. This method is complementary to the previously reported metal-catalyzed C–H amination systems. American Chemical Society 2014-04-15 2014-05-16 /pmc/articles/PMC4033662/ /pubmed/24735227 http://dx.doi.org/10.1021/jo5003592 Text en Copyright © 2014 American Chemical Society
spellingShingle Xu, Hui
Qiao, Xixue
Yang, Shiping
Shen, Zengming
Cu-Catalyzed Direct Amidation of Aromatic C–H Bonds: An Access to Arylamines
title Cu-Catalyzed Direct Amidation of Aromatic C–H Bonds: An Access to Arylamines
title_full Cu-Catalyzed Direct Amidation of Aromatic C–H Bonds: An Access to Arylamines
title_fullStr Cu-Catalyzed Direct Amidation of Aromatic C–H Bonds: An Access to Arylamines
title_full_unstemmed Cu-Catalyzed Direct Amidation of Aromatic C–H Bonds: An Access to Arylamines
title_short Cu-Catalyzed Direct Amidation of Aromatic C–H Bonds: An Access to Arylamines
title_sort cu-catalyzed direct amidation of aromatic c–h bonds: an access to arylamines
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033662/
https://www.ncbi.nlm.nih.gov/pubmed/24735227
http://dx.doi.org/10.1021/jo5003592
work_keys_str_mv AT xuhui cucatalyzeddirectamidationofaromaticchbondsanaccesstoarylamines
AT qiaoxixue cucatalyzeddirectamidationofaromaticchbondsanaccesstoarylamines
AT yangshiping cucatalyzeddirectamidationofaromaticchbondsanaccesstoarylamines
AT shenzengming cucatalyzeddirectamidationofaromaticchbondsanaccesstoarylamines

Ejemplares similares