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The late endosomal p14–MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration

Cell migration is mediated by the dynamic remodeling of focal adhesions (FAs). Recently, an important role of endosomal signaling in regulation of cell migration was recognized. Here, we show an essential function for late endosomes carrying the p14–MP1 (LAMTOR2/3) complex in FA dynamics. p14–MP1-po...

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Detalles Bibliográficos
Autores principales: Schiefermeier, Natalia, Scheffler, Julia M., de Araujo, Mariana E.G., Stasyk, Taras, Yordanov, Teodor, Ebner, Hannes L., Offterdinger, Martin, Munck, Sebastian, Hess, Michael W., Wickström, Sara A., Lange, Anika, Wunderlich, Winfried, Fässler, Reinhard, Teis, David, Huber, Lukas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033770/
https://www.ncbi.nlm.nih.gov/pubmed/24841562
http://dx.doi.org/10.1083/jcb.201310043