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The late endosomal p14–MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration
Cell migration is mediated by the dynamic remodeling of focal adhesions (FAs). Recently, an important role of endosomal signaling in regulation of cell migration was recognized. Here, we show an essential function for late endosomes carrying the p14–MP1 (LAMTOR2/3) complex in FA dynamics. p14–MP1-po...
Autores principales: | Schiefermeier, Natalia, Scheffler, Julia M., de Araujo, Mariana E.G., Stasyk, Taras, Yordanov, Teodor, Ebner, Hannes L., Offterdinger, Martin, Munck, Sebastian, Hess, Michael W., Wickström, Sara A., Lange, Anika, Wunderlich, Winfried, Fässler, Reinhard, Teis, David, Huber, Lukas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033770/ https://www.ncbi.nlm.nih.gov/pubmed/24841562 http://dx.doi.org/10.1083/jcb.201310043 |
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