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Mammalian microtubule P-body dynamics are mediated by nesprin-1

Nesprins are a multi-isomeric family of spectrin-repeat (SR) proteins, predominantly known as nuclear envelope scaffolds. However, isoforms that function beyond the nuclear envelope remain poorly examined. Here, we characterize p50(Nesp1), a 50-kD isoform that localizes to processing bodies (PBs), w...

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Detalles Bibliográficos
Autores principales: Rajgor, Dipen, Mellad, Jason A., Soong, Daniel, Rattner, Jerome B., Fritzler, Marvin J., Shanahan, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033771/
https://www.ncbi.nlm.nih.gov/pubmed/24862572
http://dx.doi.org/10.1083/jcb.201306076