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A TOGL domain specifically targets yeast CLASP to kinetochores to stabilize kinetochore microtubules

Cytoplasmic linker–associated proteins (CLASPs) are proposed to function in cell division based on their ability to bind tubulin via arrayed tumor overexpressed gene (TOG)–like (TOGL) domains. Structure predictions suggest that CLASPs have at least two TOGL domains. We show that only TOGL2 of Saccha...

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Detalles Bibliográficos
Autores principales: Funk, Caroline, Schmeiser, Verena, Ortiz, Jennifer, Lechner, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033772/
https://www.ncbi.nlm.nih.gov/pubmed/24862575
http://dx.doi.org/10.1083/jcb.201310018