CENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status

The RZZ (Rod, ZW10, and Zwilch) complex and Mad1 proteins tightly associate with kinetochores to generate the spindle checkpoint signal, but they are released when a kinetochore forms mature microtubule attachments. Here we demonstrate that the centromere protein CENP-I is required to generate a sta...

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Detalles Bibliográficos
Autores principales: Matson, Daniel R., Stukenberg, P. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033774/
https://www.ncbi.nlm.nih.gov/pubmed/24862574
http://dx.doi.org/10.1083/jcb.201307137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033774/
https://www.ncbi.nlm.nih.gov/pubmed/24862574
http://dx.doi.org/10.1083/jcb.201307137

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