Quality control on the frontier

In the world of high-throughput sequencing there are numerous challenges to effective data quality control. There are no single quality metrics which are appropriate in all conditions. Here we detail the different open source software used at the Exeter Sequencing Service to provide generic quality...

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Detalles Bibliográficos
Autores principales: Paszkiewicz, Konrad H., Farbos, Audrey, O'Neill, Paul, Moore, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033843/
https://www.ncbi.nlm.nih.gov/pubmed/24904650
http://dx.doi.org/10.3389/fgene.2014.00157
Descripción
Sumario:In the world of high-throughput sequencing there are numerous challenges to effective data quality control. There are no single quality metrics which are appropriate in all conditions. Here we detail the different open source software used at the Exeter Sequencing Service to provide generic quality control information, as well as more specific metrics for genomic and transcriptomic libraries run on Illumina platforms.

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