Quality control on the frontier

In the world of high-throughput sequencing there are numerous challenges to effective data quality control. There are no single quality metrics which are appropriate in all conditions. Here we detail the different open source software used at the Exeter Sequencing Service to provide generic quality...

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Detalles Bibliográficos
Autores principales: Paszkiewicz, Konrad H., Farbos, Audrey, O'Neill, Paul, Moore, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033843/
https://www.ncbi.nlm.nih.gov/pubmed/24904650
http://dx.doi.org/10.3389/fgene.2014.00157
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author Paszkiewicz, Konrad H.
Farbos, Audrey
O'Neill, Paul
Moore, Karen
author_facet Paszkiewicz, Konrad H.
Farbos, Audrey
O'Neill, Paul
Moore, Karen
author_sort Paszkiewicz, Konrad H.
collection PubMed
description In the world of high-throughput sequencing there are numerous challenges to effective data quality control. There are no single quality metrics which are appropriate in all conditions. Here we detail the different open source software used at the Exeter Sequencing Service to provide generic quality control information, as well as more specific metrics for genomic and transcriptomic libraries run on Illumina platforms.
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spelling pubmed-40338432014-06-05 Quality control on the frontier Paszkiewicz, Konrad H. Farbos, Audrey O'Neill, Paul Moore, Karen Front Genet Genetics In the world of high-throughput sequencing there are numerous challenges to effective data quality control. There are no single quality metrics which are appropriate in all conditions. Here we detail the different open source software used at the Exeter Sequencing Service to provide generic quality control information, as well as more specific metrics for genomic and transcriptomic libraries run on Illumina platforms. Frontiers Media S.A. 2014-05-27 /pmc/articles/PMC4033843/ /pubmed/24904650 http://dx.doi.org/10.3389/fgene.2014.00157 Text en Copyright © 2014 Paszkiewicz, Farbos, O'Neill and Moore. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Paszkiewicz, Konrad H.
Farbos, Audrey
O'Neill, Paul
Moore, Karen
Quality control on the frontier
title Quality control on the frontier
title_full Quality control on the frontier
title_fullStr Quality control on the frontier
title_full_unstemmed Quality control on the frontier
title_short Quality control on the frontier
title_sort quality control on the frontier
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033843/
https://www.ncbi.nlm.nih.gov/pubmed/24904650
http://dx.doi.org/10.3389/fgene.2014.00157
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