Incidence of amlodipine-induced gingival overgrowth in the rural population of Loni

AIMS: Since the incidence of gingival overgrowth induced by amlodipine remains poorly defined, this study was carried out with an aim to determine the incidence. MATERIALS AND METHODS: Dental patients who received amlodipine (N = 115), for more than 3 months were studied to determine the drug-induce...

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Detalles Bibliográficos
Autores principales: Tejnani, Avneesh, Mani, Ameet, Sodhi, Neha Kaur, Mehta, Alok, Gourkhede, Sonal, Thorat, Vinayak, Marawar, Pramod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4033891/
https://www.ncbi.nlm.nih.gov/pubmed/24872633
http://dx.doi.org/10.4103/0972-124X.131332
Descripción
Sumario:AIMS: Since the incidence of gingival overgrowth induced by amlodipine remains poorly defined, this study was carried out with an aim to determine the incidence. MATERIALS AND METHODS: Dental patients who received amlodipine (N = 115), for more than 3 months were studied to determine the drug-induced gingival overgrowth. Clinical diagnosis of drug-induced overgrowth was verified by disappearance or decreased severity of gingival overgrowth after withdrawal of the causative drug. RESULTS: The prevalence rate of amlodipine-induced gingival hyperplasia among experimental patients was 3.4%, while it was not observed among the control subjects. Oral examination revealed gingival overgrowth as a lobular or nodular enlargement on interdental papilla located in the anterior interproximal regions. CONCLUSIONS: In this study, there was a significant relationship between gingival inflammation resulting from dental plaque and drug dosage, and hyperplasia.

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