Cargando…
Malaria drives T cells to exhaustion
Malaria is a significant global burden but after >30 years of effort there is no vaccine on the market. While the complex life cycle of the parasite presents several challenges, many years of research have also identified several mechanisms of immune evasion by Plasmodium spp. Recent research on...
Autores principales: | Wykes, Michelle N., Horne-Debets, Joshua M., Leow, Chiuan-Yee, Karunarathne, Deshapriya S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034037/ https://www.ncbi.nlm.nih.gov/pubmed/24904561 http://dx.doi.org/10.3389/fmicb.2014.00249 |
Ejemplares similares
-
The Contribution of Co-signaling Pathways to Anti-malarial T Cell Immunity
por: Faleiro, Rebecca, et al.
Publicado: (2018) -
Mice lacking Programmed cell death-1 show a role for CD8(+) T cells in long-term immunity against blood-stage malaria
por: Horne-Debets, Joshua M., et al.
Publicado: (2016) -
A Peptide-Based PD1 Antagonist Enhances T-Cell Priming and Efficacy of a Prophylactic Malaria Vaccine and Promotes Survival in a Lethal Malaria Model
por: Phares, Timothy W., et al.
Publicado: (2020) -
Crohn's disease is facilitated by a disturbance of programmed death‐1 ligand 2 on blood dendritic cells
por: Faleiro, Rebecca, et al.
Publicado: (2019) -
Phenotypic Evidence of T Cell Exhaustion and Senescence During Symptomatic Plasmodium falciparum Malaria
por: Frimpong, Augustina, et al.
Publicado: (2019)