Allosteric Modulation of Muscarinic Acetylcholine Receptors

An allosteric modulator is a ligand that binds to an allosteric site on the receptor and changes receptor conformation to produce increase (positive cooperativity) or decrease (negative cooperativity) in the binding or action of an orthosteric agonist (e.g., acetylcholine). Since the identification...

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Detalles Bibliográficos
Autores principales: Jakubík, Jan, El-Fakahany, Esam E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034100/
https://www.ncbi.nlm.nih.gov/pubmed/27713379
http://dx.doi.org/10.3390/ph3092838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034100/
https://www.ncbi.nlm.nih.gov/pubmed/27713379
http://dx.doi.org/10.3390/ph3092838

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