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Design and physicochemical characterisation of novel dissolving polymeric microneedle arrays for transdermal delivery of high dose, low molecular weight drugs

We describe formulation and evaluation of novel dissolving polymeric microneedle (MN) arrays for the facilitated delivery of low molecular weight, high dose drugs. Ibuprofen sodium was used as the model here and was successfully formulated at approximately 50% w/w in the dry state using the copolyme...

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Detalles Bibliográficos
Autores principales:	McCrudden, Maelíosa T.C., Alkilani, Ahlam Zaid, McCrudden, Cian M., McAlister, Emma, McCarthy, Helen O., Woolfson, A. David, Donnelly, Ryan F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Publishers 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034161/ https://www.ncbi.nlm.nih.gov/pubmed/24556420 http://dx.doi.org/10.1016/j.jconrel.2014.02.007

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