Suppressive Effect of High Hydrogen Generating High Amylose Cornstarch on Subacute Hepatic Ischemia-reperfusion Injury in Rats

We examined whether feeding high hydrogen generating resistant starch could suppress subacute hepatic ischemia-reperfusion injury. Rats were fed a control diet with or without 20% high amylose cornstarch (HAS) supplementation for 14 days. On day 12, rats were subject to ischemia-reperfusion treatmen...

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Autores principales: TANABE, Hiroki, SASAKI, Yumi, YAMAMOTO, Tatsuro, KIRIYAMA, Shuhachi, NISHIMURA, Naomichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscience of Microbiota, Food and Health 2012
Materias:
Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034286/
https://www.ncbi.nlm.nih.gov/pubmed/24936356
http://dx.doi.org/10.12938/bmfh.31.103
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author TANABE, Hiroki
SASAKI, Yumi
YAMAMOTO, Tatsuro
KIRIYAMA, Shuhachi
NISHIMURA, Naomichi
author_facet TANABE, Hiroki
SASAKI, Yumi
YAMAMOTO, Tatsuro
KIRIYAMA, Shuhachi
NISHIMURA, Naomichi
author_sort TANABE, Hiroki
collection PubMed
description We examined whether feeding high hydrogen generating resistant starch could suppress subacute hepatic ischemia-reperfusion injury. Rats were fed a control diet with or without 20% high amylose cornstarch (HAS) supplementation for 14 days. On day 12, rats were subject to ischemia-reperfusion treatment. Portal hydrogen concentration was higher in the HAS group compared with the control group. Increased plasma alanine and aspartate aminotransferase activities due to ischemia-reperfusion treatment tended to decrease, and a significant reduction was observed by HAS feeding when compared with the control group. In conclusion, HAS, which enhances hydrogen generation in the hindgut, alleviated subacute hepatic ischemia-reperfusion injury.
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spelling pubmed-40342862014-06-16 Suppressive Effect of High Hydrogen Generating High Amylose Cornstarch on Subacute Hepatic Ischemia-reperfusion Injury in Rats TANABE, Hiroki SASAKI, Yumi YAMAMOTO, Tatsuro KIRIYAMA, Shuhachi NISHIMURA, Naomichi Biosci Microbiota Food Health Note We examined whether feeding high hydrogen generating resistant starch could suppress subacute hepatic ischemia-reperfusion injury. Rats were fed a control diet with or without 20% high amylose cornstarch (HAS) supplementation for 14 days. On day 12, rats were subject to ischemia-reperfusion treatment. Portal hydrogen concentration was higher in the HAS group compared with the control group. Increased plasma alanine and aspartate aminotransferase activities due to ischemia-reperfusion treatment tended to decrease, and a significant reduction was observed by HAS feeding when compared with the control group. In conclusion, HAS, which enhances hydrogen generation in the hindgut, alleviated subacute hepatic ischemia-reperfusion injury. Bioscience of Microbiota, Food and Health 2012-10-25 2012 /pmc/articles/PMC4034286/ /pubmed/24936356 http://dx.doi.org/10.12938/bmfh.31.103 Text en Bioscience of Microbiota, Food and Health http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Note
TANABE, Hiroki
SASAKI, Yumi
YAMAMOTO, Tatsuro
KIRIYAMA, Shuhachi
NISHIMURA, Naomichi
Suppressive Effect of High Hydrogen Generating High Amylose Cornstarch on Subacute Hepatic Ischemia-reperfusion Injury in Rats
title Suppressive Effect of High Hydrogen Generating High Amylose Cornstarch on Subacute Hepatic Ischemia-reperfusion Injury in Rats
title_full Suppressive Effect of High Hydrogen Generating High Amylose Cornstarch on Subacute Hepatic Ischemia-reperfusion Injury in Rats
title_fullStr Suppressive Effect of High Hydrogen Generating High Amylose Cornstarch on Subacute Hepatic Ischemia-reperfusion Injury in Rats
title_full_unstemmed Suppressive Effect of High Hydrogen Generating High Amylose Cornstarch on Subacute Hepatic Ischemia-reperfusion Injury in Rats
title_short Suppressive Effect of High Hydrogen Generating High Amylose Cornstarch on Subacute Hepatic Ischemia-reperfusion Injury in Rats
title_sort suppressive effect of high hydrogen generating high amylose cornstarch on subacute hepatic ischemia-reperfusion injury in rats
topic Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034286/
https://www.ncbi.nlm.nih.gov/pubmed/24936356
http://dx.doi.org/10.12938/bmfh.31.103
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