In Silico Design of BACE1 Inhibitor for Alzheimer's Disease by Traditional Chinese Medicine

The β-site APP cleaving enzyme 1 (BACE1) is an important target for causing Alzheimer's disease (AD), due to the brain deposition peptide amyloid beta (Aβ) require cleavages of amyloid precursor protein (APP) by BACE1 and γ-secretase, but treatments of AD still have side effect in recent therap...

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Detalles Bibliográficos
Autores principales: Huang, Hung-Jin, Lee, Cheng-Chun, Chen, Calvin Yu-Chian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034430/
https://www.ncbi.nlm.nih.gov/pubmed/24900984
http://dx.doi.org/10.1155/2014/741703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034430/
https://www.ncbi.nlm.nih.gov/pubmed/24900984
http://dx.doi.org/10.1155/2014/741703

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