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In Silico Design of BACE1 Inhibitor for Alzheimer's Disease by Traditional Chinese Medicine
The β-site APP cleaving enzyme 1 (BACE1) is an important target for causing Alzheimer's disease (AD), due to the brain deposition peptide amyloid beta (Aβ) require cleavages of amyloid precursor protein (APP) by BACE1 and γ-secretase, but treatments of AD still have side effect in recent therap...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034430/ https://www.ncbi.nlm.nih.gov/pubmed/24900984 http://dx.doi.org/10.1155/2014/741703 |