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Involvement of the Circadian Rhythm and Inflammatory Cytokines in the Pathogenesis of Rheumatoid Arthritis
Among the symptoms of patients with rheumatoid arthritis (RA), joint stiffness is influenced by diurnal rhythm and reaches peak in the morning, which is a common complaint and reflects the circadian nature of disease manifestation. In addition, inflammatory cytokines, which reach peak secretion earl...
Autores principales: | Yoshida, Kohsuke, Hashimoto, Teppei, Sakai, Yoshitada, Hashiramoto, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034483/ https://www.ncbi.nlm.nih.gov/pubmed/24901009 http://dx.doi.org/10.1155/2014/282495 |
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