Mutation Analysis of JAK2V617F, FLT3-ITD, NPM1, and DNMT3A in Chinese Patients with Myeloproliferative Neoplasms

Since the discovery of JAK2V617F tyrosine kinase-activating mutation, several genes have been found mutated in myeloproliferative neoplasms (MPNs). FLT3-ITD, NPM1, and DNMT3A mutations frequently occurred in AML patients and have been found conferred with myeloproliferative neoplasms in mouse model....

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Detalles Bibliográficos
Autores principales: Wang, Min, He, Na, Tian, Tian, Liu, Lu, Yu, Shuang, Ma, Daoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034537/
https://www.ncbi.nlm.nih.gov/pubmed/24895580
http://dx.doi.org/10.1155/2014/485645

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