Whole exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

Comprehensive analyses of cancer genomes promise to inform prognoses and precise cancer treatments. A major barrier, however, is inaccessibility of metastatic tissue. A potential solution is to characterize circulating tumor cells (CTCs), but this requires overcoming the challenges of isolating rare...

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Detalles Bibliográficos
Autores principales: Lohr, Jens G., Adalsteinsson, Viktor A., Cibulskis, Kristian, Choudhury, Atish D., Rosenberg, Mara, Cruz-Gordillo, Peter, Francis, Joshua, Zhang, Cheng-Zhong, Shalek, Alex K., Satija, Rahul, Trombetta, John T., Lu, Diana, Tallapragada, Naren, Tahirova, Narmin, Kim, Sora, Blumenstiel, Brendan, Sougnez, Carrie, Lowe, Alarice, Wong, Bang, Auclair, Daniel, Van Allen, Eliezer M., Nakabayashi, Mari, Lis, Rosina T., Lee, Gwo-Shu M., Li, Tiantian, Chabot, Matthew S., Ly, Amy, Taplin, Mary-Ellen, Clancy, Thomas E., Loda, Massimo, Regev, Aviv, Meyerson, Matthew, Hahn, William C., Kantoff, Philip W., Golub, Todd R., Getz, Gad, Boehm, Jesse S., Love, J. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034575/
https://www.ncbi.nlm.nih.gov/pubmed/24752078
http://dx.doi.org/10.1038/nbt.2892

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