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Langerhans Cell Histiocytosis: An Illusion of Hope

Introduction: Langerhans cell histiocytosis (LCH) is a rare atypical cellular disorder characterized by clonal proliferation of Langerhans cells leading to myriad clinical presentations and variable outcomes. It usually occurs in children and young adults. It can be present with local and systemic m...

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Autores principales: Desai, Vela D, Priyadarshinni, Smita R, Varma, Beena, Sharma, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034643/
https://www.ncbi.nlm.nih.gov/pubmed/25206193
http://dx.doi.org/10.5005/jp-journals-10005-1191
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author Desai, Vela D
Priyadarshinni, Smita R
Varma, Beena
Sharma, Rajeev
author_facet Desai, Vela D
Priyadarshinni, Smita R
Varma, Beena
Sharma, Rajeev
author_sort Desai, Vela D
collection PubMed
description Introduction: Langerhans cell histiocytosis (LCH) is a rare atypical cellular disorder characterized by clonal proliferation of Langerhans cells leading to myriad clinical presentations and variable outcomes. It usually occurs in children and young adults. It can be present with local and systemic manifestation involving skin, bone, mucosal tissues and internal organs. Aims and objectives: The stomatologist plays an important role in management of the disease by keeping in mind the various oral manifestations of the disease. Case report: Of a child with disseminated LCH with multiorgan involvement who presented with failure to thrive, osteolytic bony lesions and extensive cutaneous eruptions. Conclusion: Early diagnosis and awareness is necessary to treat the patients. How to cite this article: Desai VD, Priyadarshinni SR, Varma B, Sharma R. Langerhans Cell Histiocytosis: An Illusion of Hope. Int J Clin Pediatr Dent 2013;6(1):66-70.
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spelling pubmed-40346432014-09-09 Langerhans Cell Histiocytosis: An Illusion of Hope Desai, Vela D Priyadarshinni, Smita R Varma, Beena Sharma, Rajeev Int J Clin Pediatr Dent Case Report Introduction: Langerhans cell histiocytosis (LCH) is a rare atypical cellular disorder characterized by clonal proliferation of Langerhans cells leading to myriad clinical presentations and variable outcomes. It usually occurs in children and young adults. It can be present with local and systemic manifestation involving skin, bone, mucosal tissues and internal organs. Aims and objectives: The stomatologist plays an important role in management of the disease by keeping in mind the various oral manifestations of the disease. Case report: Of a child with disseminated LCH with multiorgan involvement who presented with failure to thrive, osteolytic bony lesions and extensive cutaneous eruptions. Conclusion: Early diagnosis and awareness is necessary to treat the patients. How to cite this article: Desai VD, Priyadarshinni SR, Varma B, Sharma R. Langerhans Cell Histiocytosis: An Illusion of Hope. Int J Clin Pediatr Dent 2013;6(1):66-70. Jaypee Brothers Medical Publishers 2013 2013-04-26 /pmc/articles/PMC4034643/ /pubmed/25206193 http://dx.doi.org/10.5005/jp-journals-10005-1191 Text en Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd. This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/
spellingShingle Case Report
Desai, Vela D
Priyadarshinni, Smita R
Varma, Beena
Sharma, Rajeev
Langerhans Cell Histiocytosis: An Illusion of Hope
title Langerhans Cell Histiocytosis: An Illusion of Hope
title_full Langerhans Cell Histiocytosis: An Illusion of Hope
title_fullStr Langerhans Cell Histiocytosis: An Illusion of Hope
title_full_unstemmed Langerhans Cell Histiocytosis: An Illusion of Hope
title_short Langerhans Cell Histiocytosis: An Illusion of Hope
title_sort langerhans cell histiocytosis: an illusion of hope
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034643/
https://www.ncbi.nlm.nih.gov/pubmed/25206193
http://dx.doi.org/10.5005/jp-journals-10005-1191
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