Alkylation of Histidine Residues of Bothrops jararacussu Venom Proteins and Isolated Phospholipases A(2): A Biotechnological Tool to Improve the Production of Antibodies

Crude venom of Bothrops jararacussu and isolated phospholipases A(2) (PLA(2)) of this toxin (BthTX-I and BthTX-II) were chemically modified (alkylation) by p-bromophenacyl bromide (BPB) in order to study antibody production capacity in function of the structure-function relationship of these substan...

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Detalles Bibliográficos
Autores principales: Guimarães, C. L. S., Andrião-Escarso, S. H., Moreira-Dill, L. S., Carvalho, B. M. A., Marchi-Salvador, D. P., Santos-Filho, N. A., Fernandes, C. A. H., Fontes, M. R. M., Giglio, J. R., Barraviera, B., Zuliani, J. P., Fernandes, C. F. C., Calderón, L. A., Stábeli, R. G., Albericio, F., da Silva, S. L., Soares, A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034654/
https://www.ncbi.nlm.nih.gov/pubmed/24901004
http://dx.doi.org/10.1155/2014/981923

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