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Epidemiologic and Demographic Survey of Celiac Disease in Khuzestan Province
BACKGROUND Celiac disease presents with a wide spectrum of symptoms. This study clarifies different aspects of celiac disease along with the most common patterns of celiac presentation in Khuzestan Province, Iran. METHODS Patients’ information was obtained by evaluation of their files from the archi...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Iranian Association of Gastroerterology and Hepatology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034671/ https://www.ncbi.nlm.nih.gov/pubmed/24872869 |
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author | Alavinejad, Pezhman Hajiani, Eskandar Masjedizadeh, Rahim Hashemi, Seyed Jalal Faramarzi, Mohammad Sebghatollahi, Vahid Shayesteh, Ali Akbar Kadkhodae, Ahmad Jasemi Zergani, Farzad Asghari, Shahnaz Farsi, Farnaz |
author_facet | Alavinejad, Pezhman Hajiani, Eskandar Masjedizadeh, Rahim Hashemi, Seyed Jalal Faramarzi, Mohammad Sebghatollahi, Vahid Shayesteh, Ali Akbar Kadkhodae, Ahmad Jasemi Zergani, Farzad Asghari, Shahnaz Farsi, Farnaz |
author_sort | Alavinejad, Pezhman |
collection | PubMed |
description | BACKGROUND Celiac disease presents with a wide spectrum of symptoms. This study clarifies different aspects of celiac disease along with the most common patterns of celiac presentation in Khuzestan Province, Iran. METHODS Patients’ information was obtained by evaluation of their files from the archives of the Khuzestan Celiac Society and records at gastroenterologists’ offices in this province. RESULTS Overall, there were 103 (40 males, 63 females) patients included in this study. Patients’ mean ages were 33 ± 11 years (males) and 31.6 ± 11.7 years (females). In terms of geographic distribution, 54.1% resided in the center of the province followed by 26.5% who were residents of the northern area. The rate of employment among men was 70.6% whereas it was 8.3% for women. In terms of education, 21.9% of men and 33.3% of women had academic educations. The rate of matrimony was 80.6% (n=29) for men, 65.4% (n=38) for women and 3.4% (n=2) who were divorced. Mean height was 164 ± 14 cm in men and 157.5 ± 10 cm in women. Mean BMI at the time of presentation was 22.7 in men and 22.6 in women. The most common gastrointestinal (GI) complaints in male patients were diarrhea (35%), reflux (20%), bloating (17.5%), abdominal pain (15%), vomiting (15%) and constipation (7.5%). Female patients experienced diarrhea (49.2%), abdominal pain (31.7%), bloating (31.7%), vomiting (19%), constipation(9.5%) and reflux (7.9%). The most common concomitant non-GI disorders among male patients were anemia (17.1%), thyroid disease (14.3%), and weight loss (14.3%); women experienced anemia (33.9%), thyroid disease (12.5%), and weight loss (7.1%). Approximately half of the patients exhibited symptoms for more than five years prior to diagnosis and 90% were diagnosed by gastroenterologists. Of these, 43% had normal endoscopy results. The most common serologic markers were anti-TTG (69.9%), anti-EMA (27.7%). CONCLUSION Physicians, prior to attributing patients’ symptoms to irritable bowel syndrome (IBS), should be aware that patients who present with long-term nonspecific symptoms might possibly have celiac disease. During endoscopy, the threshold for obtaining biopsies should be low. |
format | Online Article Text |
id | pubmed-4034671 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Iranian Association of Gastroerterology and Hepatology |
record_format | MEDLINE/PubMed |
spelling | pubmed-40346712014-05-28 Epidemiologic and Demographic Survey of Celiac Disease in Khuzestan Province Alavinejad, Pezhman Hajiani, Eskandar Masjedizadeh, Rahim Hashemi, Seyed Jalal Faramarzi, Mohammad Sebghatollahi, Vahid Shayesteh, Ali Akbar Kadkhodae, Ahmad Jasemi Zergani, Farzad Asghari, Shahnaz Farsi, Farnaz Middle East J Dig Dis Original Article BACKGROUND Celiac disease presents with a wide spectrum of symptoms. This study clarifies different aspects of celiac disease along with the most common patterns of celiac presentation in Khuzestan Province, Iran. METHODS Patients’ information was obtained by evaluation of their files from the archives of the Khuzestan Celiac Society and records at gastroenterologists’ offices in this province. RESULTS Overall, there were 103 (40 males, 63 females) patients included in this study. Patients’ mean ages were 33 ± 11 years (males) and 31.6 ± 11.7 years (females). In terms of geographic distribution, 54.1% resided in the center of the province followed by 26.5% who were residents of the northern area. The rate of employment among men was 70.6% whereas it was 8.3% for women. In terms of education, 21.9% of men and 33.3% of women had academic educations. The rate of matrimony was 80.6% (n=29) for men, 65.4% (n=38) for women and 3.4% (n=2) who were divorced. Mean height was 164 ± 14 cm in men and 157.5 ± 10 cm in women. Mean BMI at the time of presentation was 22.7 in men and 22.6 in women. The most common gastrointestinal (GI) complaints in male patients were diarrhea (35%), reflux (20%), bloating (17.5%), abdominal pain (15%), vomiting (15%) and constipation (7.5%). Female patients experienced diarrhea (49.2%), abdominal pain (31.7%), bloating (31.7%), vomiting (19%), constipation(9.5%) and reflux (7.9%). The most common concomitant non-GI disorders among male patients were anemia (17.1%), thyroid disease (14.3%), and weight loss (14.3%); women experienced anemia (33.9%), thyroid disease (12.5%), and weight loss (7.1%). Approximately half of the patients exhibited symptoms for more than five years prior to diagnosis and 90% were diagnosed by gastroenterologists. Of these, 43% had normal endoscopy results. The most common serologic markers were anti-TTG (69.9%), anti-EMA (27.7%). CONCLUSION Physicians, prior to attributing patients’ symptoms to irritable bowel syndrome (IBS), should be aware that patients who present with long-term nonspecific symptoms might possibly have celiac disease. During endoscopy, the threshold for obtaining biopsies should be low. Iranian Association of Gastroerterology and Hepatology 2014-04 /pmc/articles/PMC4034671/ /pubmed/24872869 Text en © 2014 by Middle East Journal of Digestive Diseases This work is published by Middle East Journal of Digestive Diseases as an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-sa/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited. |
spellingShingle | Original Article Alavinejad, Pezhman Hajiani, Eskandar Masjedizadeh, Rahim Hashemi, Seyed Jalal Faramarzi, Mohammad Sebghatollahi, Vahid Shayesteh, Ali Akbar Kadkhodae, Ahmad Jasemi Zergani, Farzad Asghari, Shahnaz Farsi, Farnaz Epidemiologic and Demographic Survey of Celiac Disease in Khuzestan Province |
title | Epidemiologic and Demographic Survey of Celiac Disease in Khuzestan Province |
title_full | Epidemiologic and Demographic Survey of Celiac Disease in Khuzestan Province |
title_fullStr | Epidemiologic and Demographic Survey of Celiac Disease in Khuzestan Province |
title_full_unstemmed | Epidemiologic and Demographic Survey of Celiac Disease in Khuzestan Province |
title_short | Epidemiologic and Demographic Survey of Celiac Disease in Khuzestan Province |
title_sort | epidemiologic and demographic survey of celiac disease in khuzestan province |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034671/ https://www.ncbi.nlm.nih.gov/pubmed/24872869 |
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