Cargando…

Piperlongumine Induces Apoptosis and Synergizes with Cisplatin or Paclitaxel in Human Ovarian Cancer Cells

Piperlongumine (PL), a natural alkaloid from Piper longum L., possesses the highly selective and effective anticancer property. However, the effect of PL on ovarian cancer cells is still unknown. In this study, we firstly demonstrate that PL selectively inhibited cell growth of human ovarian cancer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gong, Li-Hua, Chen, Xiu-Xiu, Wang, Huan, Jiang, Qi-Wei, Pan, Shi-Shi, Qiu, Jian-Ge, Mei, Xiao-Long, Xue, You-Qiu, Qin, Wu-Ming, Zheng, Fei-Yun, Shi, Zhi, Yan, Xiao-Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034765/ https://www.ncbi.nlm.nih.gov/pubmed/24895529 http://dx.doi.org/10.1155/2014/906804

Ejemplares similares

Cyclin-dependent kinase inhibitor dinaciclib potently synergizes with cisplatin in preclinical models of ovarian cancer
por: Chen, Xiu-Xiu, et al.
Publicado: (2015)

Survivin Promotes Piperlongumine Resistance in Ovarian Cancer
por: Nan, Xing-Wei, et al.
Publicado: (2019)

Sulforaphane regulates apoptosis- and proliferation-related signaling pathways and synergizes with cisplatin to suppress human ovarian cancer
por: Kan, Shi-Feng, et al.
Publicado: (2018)

Piperlongumine and immune cytokine TRAIL synergize to promote tumor death
por: Li, Jiahe, et al.
Publicado: (2015)

Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells
por: Scharer, Christopher D, et al.
Publicado: (2008)

Identification of Piperlongumine as Potent Inhibitor of Necroptosis
por: He, Xiaoyan, et al.
Publicado: (2023)

Piperlongumine inhibits migration and proliferation of castration-resistant prostate cancer cells via triggering persistent DNA damage
por: Zhang, Ding-fang, et al.
Publicado: (2021)

Piperlongumine Induces Apoptosis and Synergizes with Doxorubicin by Inhibiting the JAK2-STAT3 Pathway in Triple-Negative Breast Cancer
por: Chen, Di, et al.
Publicado: (2019)

Piperlongumine increases the sensitivity of bladder cancer to cisplatin by mitochondrial ROS
por: Pan, Xiaobo, et al.
Publicado: (2022)

Low-dose paclitaxel synergizes with oncolytic adenoviruses via mitotic slippage and apoptosis in ovarian cancer
por: Ingemarsdotter, C K, et al.
Publicado: (2010)

NVP-BEZ235 synergizes cisplatin sensitivity in osteosarcoma
por: Huang, Jin-Cheng, et al.
Publicado: (2017)

CRM197 reverses paclitaxel resistance by inhibiting the NAC‐1/Gadd45 pathway in paclitaxel‐resistant ovarian cancer cells
por: Tang, Xiao‐han, et al.
Publicado: (2019)

Piperlongumine Alleviates Mouse Colitis and Colitis-Associated Colorectal Cancer
por: Huang, Jia-Rong, et al.
Publicado: (2020)

Piperlongumine Is an NLRP3 Inhibitor With Anti-inflammatory Activity
por: Shi, Jie, et al.
Publicado: (2022)

Piperlongumine induces apoptosis and reduces bortezomib resistance by inhibiting STAT3 in multiple myeloma cells
por: Yao, Yao, et al.
Publicado: (2016)

Preformulation Studies on Piperlongumine
por: Aodah, Alhassan, et al.
Publicado: (2016)

Synergic effect between 5-fluorouracil and celecoxib on hypoxic gastric cancer cells
por: Zhang, Xiao-Qian, et al.
Publicado: (2021)

Piperlongumine Analogs Promote A549 Cell Apoptosis through Enhancing ROS Generation
por: Sun, Ai-Ling, et al.
Publicado: (2021)

Piperlongumine Attenuates High Calcium/Phosphate-Induced Arterial Calcification by Preserving P53/PTEN Signaling
por: Shi, Wenxiang, et al.
Publicado: (2021)

MicroRNA-137 inhibits tumor growth and sensitizes chemosensitivity to paclitaxel and cisplatin in lung cancer
por: Shen, Hua, et al.
Publicado: (2016)

Effects of paclitaxel and cisplatin on in vitro ovarian follicle development
por: Kim, Yoon Young, et al.
Publicado: (2019)

Paclitaxel Induce Apoptosis of Giant Cells Tumor of Bone via TP53INP1 Signaling
por: Xiao, Wei‐Yuan, et al.
Publicado: (2018)

Piperlongumine selectively kills cancer cells and increases cisplatin antitumor activity in head and neck cancer
por: Roh, Jong-Lyel, et al.
Publicado: (2014)

Manganese-deposited iron oxide promotes tumor-responsive ferroptosis that synergizes the apoptosis of cisplatin
por: Cheng, Junjie, et al.
Publicado: (2021)

Metabolic profile and safety of piperlongumine
por: de Lima Moreira, Fernanda, et al.
Publicado: (2016)

Clarithromycin synergizes with cisplatin to inhibit ovarian cancer growth in vitro and in vivo
por: Zhou, Bo, et al.
Publicado: (2019)

Piperlongumine alleviates corneal allograft rejection via suppressing angiogenesis and inflammation
por: Fan, Xiangyu, et al.
Publicado: (2022)

Piperlongumine Inhibits Migration of Glioblastoma Cells via Activation of ROS-Dependent p38 and JNK Signaling Pathways
por: Liu, Qian Rong, et al.
Publicado: (2014)

Proton pump inhibitors can reverse the YAP mediated paclitaxel resistance in epithelial ovarian cancer
por: He, Jing, et al.
Publicado: (2019)

Piperlongumine Suppresses Proliferation of Human Oral Squamous Cell Carcinoma through Cell Cycle Arrest, Apoptosis and Senescence
por: Chen, San-Yuan, et al.
Publicado: (2016)

Piperlongumine Inhibits Titanium Particles-Induced Osteolysis, Osteoclast Formation, and RANKL-Induced Signaling Pathways
por: Liu, Xuan, et al.
Publicado: (2022)

Piperlongumine Inhibits Akt Phosphorylation to Reverse Resistance to Cisplatin in Human Non-Small Cell Lung Cancer Cells via ROS Regulation
por: Zhang, Chao, et al.
Publicado: (2019)

Piperlongumine selectively kills hepatocellular carcinoma cells and preferentially inhibits their invasion via ROS-ER-MAPKs-CHOP
por: Chen, Yong, et al.
Publicado: (2015)

Piperlongumine induces autophagy by targeting p38 signaling
por: Wang, Y, et al.
Publicado: (2013)

Piperlongumine and p53-Reactivator APR-246 Selectively Induce Cell Death in HNSCC by Targeting GSTP1
por: Hang, Wei, et al.
Publicado: (2018)

First-line chemotherapy for advanced ovarian cancer: paclitaxel, cisplatin and the evidence.
por: Sandercock, J., et al.
Publicado: (1998)

Genetic polymorphisms and ovarian cancer risk and response to paclitaxel/cisplatin chemotherapy
por: Tecza, Karolina, et al.
Publicado: (2015)

Systemic exposure to cisplatin and paclitaxel after intraperitoneal chemotherapy in ovarian cancer
por: de Jong, Loek A. W., et al.
Publicado: (2023)

Piperlongumine restores the balance of autophagy and apoptosis by increasing BCL2 phosphorylation in rotenone-induced Parkinson disease models
por: Liu, Jia, et al.
Publicado: (2018)

Apatinib induces endoplasmic reticulum stress-mediated apoptosis and autophagy and potentiates cell sensitivity to paclitaxel via the IRE-1α–AKT–mTOR pathway in esophageal squamous cell carcinoma
por: Wang, Yu-Ming, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_70gs5d66k6c7akcl8atk60grmu