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Network Analyses Reveal Pervasive Functional Regulation Between Proteases in the Human Protease Web
Proteolytic processing is an irreversible posttranslational modification affecting a large portion of the proteome. Protease-cleaved mediators frequently exhibit altered activity, and biological pathways are often regulated by proteolytic processing. Many of these mechanisms have not been appreciate...
Autores principales: | Fortelny, Nikolaus, Cox, Jennifer H., Kappelhoff, Reinhild, Starr, Amanda E., Lange, Philipp F., Pavlidis, Paul, Overall, Christopher M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035269/ https://www.ncbi.nlm.nih.gov/pubmed/24865846 http://dx.doi.org/10.1371/journal.pbio.1001869 |
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