Exceptional Evolutionary Divergence of Human Muscle and Brain Metabolomes Parallels Human Cognitive and Physical Uniqueness

Metabolite concentrations reflect the physiological states of tissues and cells. However, the role of metabolic changes in species evolution is currently unknown. Here, we present a study of metabolome evolution conducted in three brain regions and two non-neural tissues from humans, chimpanzees, ma...

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Detalles Bibliográficos
Autores principales: Bozek, Katarzyna, Wei, Yuning, Yan, Zheng, Liu, Xiling, Xiong, Jieyi, Sugimoto, Masahiro, Tomita, Masaru, Pääbo, Svante, Pieszek, Raik, Sherwood, Chet C., Hof, Patrick R., Ely, John J., Steinhauser, Dirk, Willmitzer, Lothar, Bangsbo, Jens, Hansson, Ola, Call, Josep, Giavalisco, Patrick, Khaitovich, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035273/
https://www.ncbi.nlm.nih.gov/pubmed/24866127
http://dx.doi.org/10.1371/journal.pbio.1001871

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