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Copy Number Variation of the Beta Defensin Gene Cluster on Chromosome 8p Influences the Bacterial Microbiota within the Nasopharynx of Otitis-Prone Children

As there is increasing evidence that aberrant defensin expression is related to susceptibility for infectious disease and inflammatory disorders, we sought to determine if copy number of the beta-defensin gene cluster located on chromosome 8p23.1 (DEFB107, 106, 105, 104, 103, DEFB4 and SPAG11), that...

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Detalles Bibliográficos
Autores principales: Jones, Eric A., Kananurak, Anchasa, Bevins, Charles L., Hollox, Edward J., Bakaletz, Lauren O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035277/
https://www.ncbi.nlm.nih.gov/pubmed/24867293
http://dx.doi.org/10.1371/journal.pone.0098269