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An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth

The spliceosome machinery is composed of multimeric protein complexes that generate a diverse repertoire of mRNA through coordinated splicing of heteronuclear RNAs. While somatic mutations in spliceosome components have been discovered in several cancer types, the molecular bases and consequences of...

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Detalles Bibliográficos
Autores principales:	Adler, Adam S., McCleland, Mark L., Yee, Sharon, Yaylaoglu, Murat, Hussain, Sofia, Cosino, Ely, Quinones, Gabriel, Modrusan, Zora, Seshagiri, Somasekar, Torres, Eric, Chopra, Vivek S., Haley, Benjamin, Zhang, Zemin, Blackwood, Elizabeth M., Singh, Mallika, Junttila, Melissa, Stephan, Jean-Philippe, Liu, Jinfeng, Pau, Gregoire, Fearon, Eric R., Jiang, Zhaoshi, Firestein, Ron
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035536/ https://www.ncbi.nlm.nih.gov/pubmed/24788092 http://dx.doi.org/10.1101/gad.237206.113

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