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Implementation of a program for quality assurance on leaf positioning accuracy using Gafchromic(®) RTQA2 films

In radiotherapy treatments the correct dose delivery to the target volume and the consequent conservation of healthy tissues is affected by multileaf collimator (MLC) leaf positioning accuracy and reproducibility, mostly in intensity-modulated radiation therapy (IMRT): For this reason a quality assu...

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Autores principales: Girardi, Andrea, Anglesio, Silvia, Amadore, Gianluca, Trevisiol, Edoardo, Redda, Maria Grazia Ruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035615/
https://www.ncbi.nlm.nih.gov/pubmed/24872610
http://dx.doi.org/10.4103/0971-6203.131287
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author Girardi, Andrea
Anglesio, Silvia
Amadore, Gianluca
Trevisiol, Edoardo
Redda, Maria Grazia Ruo
author_facet Girardi, Andrea
Anglesio, Silvia
Amadore, Gianluca
Trevisiol, Edoardo
Redda, Maria Grazia Ruo
author_sort Girardi, Andrea
collection PubMed
description In radiotherapy treatments the correct dose delivery to the target volume and the consequent conservation of healthy tissues is affected by multileaf collimator (MLC) leaf positioning accuracy and reproducibility, mostly in intensity-modulated radiation therapy (IMRT): For this reason a quality assurance (QA) program is necessary to ensure the best treatment possible to each patient. The aim of this study is the implementation of a method using Gafchromic(®) RTQA 2 films to perform routine QA on the MLC, both for qualitative and quantitative analysis. A flatbed document scanner (Epson 10000XL) was used in conjunction with radiochromic detector; a scanning protocol was firstly defined to improve readout accuracy. RTQA2 films were irradiated with 6 MV X-rays at different dose levels to obtain calibration curve. To evaluate the leaf positioning accuracy in different conditions, a rhomboidal shape and a field consisting in three rectangular segments were selected. The images quantitative analysis was handled with a program developed in MATLAB to evaluate the differences between expected and measured leaves positions. The reproducibility and global uncertainty of the method were estimated to be equal to 0.5% and 0.6 mm, respectively. Moreover, a qualitative test was performed: A garden picket fence field, consisting in multiple segments 2 × 22 cm(2), was realized setting known leaves shifts to test the method sensitivity. The picket fence test shows that the method is able to detect displacements equal to 1 mm. The results suggest that Gafchromic(®) RTQA2 films represent a reliable tool to perform MLC routine QA.
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spelling pubmed-40356152014-05-28 Implementation of a program for quality assurance on leaf positioning accuracy using Gafchromic(®) RTQA2 films Girardi, Andrea Anglesio, Silvia Amadore, Gianluca Trevisiol, Edoardo Redda, Maria Grazia Ruo J Med Phys Technical Note In radiotherapy treatments the correct dose delivery to the target volume and the consequent conservation of healthy tissues is affected by multileaf collimator (MLC) leaf positioning accuracy and reproducibility, mostly in intensity-modulated radiation therapy (IMRT): For this reason a quality assurance (QA) program is necessary to ensure the best treatment possible to each patient. The aim of this study is the implementation of a method using Gafchromic(®) RTQA 2 films to perform routine QA on the MLC, both for qualitative and quantitative analysis. A flatbed document scanner (Epson 10000XL) was used in conjunction with radiochromic detector; a scanning protocol was firstly defined to improve readout accuracy. RTQA2 films were irradiated with 6 MV X-rays at different dose levels to obtain calibration curve. To evaluate the leaf positioning accuracy in different conditions, a rhomboidal shape and a field consisting in three rectangular segments were selected. The images quantitative analysis was handled with a program developed in MATLAB to evaluate the differences between expected and measured leaves positions. The reproducibility and global uncertainty of the method were estimated to be equal to 0.5% and 0.6 mm, respectively. Moreover, a qualitative test was performed: A garden picket fence field, consisting in multiple segments 2 × 22 cm(2), was realized setting known leaves shifts to test the method sensitivity. The picket fence test shows that the method is able to detect displacements equal to 1 mm. The results suggest that Gafchromic(®) RTQA2 films represent a reliable tool to perform MLC routine QA. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4035615/ /pubmed/24872610 http://dx.doi.org/10.4103/0971-6203.131287 Text en Copyright: © Journal of Medical Physics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Technical Note
Girardi, Andrea
Anglesio, Silvia
Amadore, Gianluca
Trevisiol, Edoardo
Redda, Maria Grazia Ruo
Implementation of a program for quality assurance on leaf positioning accuracy using Gafchromic(®) RTQA2 films
title Implementation of a program for quality assurance on leaf positioning accuracy using Gafchromic(®) RTQA2 films
title_full Implementation of a program for quality assurance on leaf positioning accuracy using Gafchromic(®) RTQA2 films
title_fullStr Implementation of a program for quality assurance on leaf positioning accuracy using Gafchromic(®) RTQA2 films
title_full_unstemmed Implementation of a program for quality assurance on leaf positioning accuracy using Gafchromic(®) RTQA2 films
title_short Implementation of a program for quality assurance on leaf positioning accuracy using Gafchromic(®) RTQA2 films
title_sort implementation of a program for quality assurance on leaf positioning accuracy using gafchromic(®) rtqa2 films
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035615/
https://www.ncbi.nlm.nih.gov/pubmed/24872610
http://dx.doi.org/10.4103/0971-6203.131287
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