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Comparative analysis of volumetric-modulated arc therapy and intensity-modulated radiotherapy for base of tongue cancer

The aim of this study was to compare the various dosimetric parameters of dynamic multileaf collimator (MLC) intensity modulated radiation therapy (IMRT) plans with volumetric modulated arc therapy (VMAT) plans for base of tongue cases. All plans were done in Monaco planning system for Elekta synerg...

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Autores principales: Nithya, L., Raj, N. Arunai Nambi, Kumar, Arulraj, Rathinamuthu, Sasikumar, Pandey, Manish Bhushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035616/
https://www.ncbi.nlm.nih.gov/pubmed/24872611
http://dx.doi.org/10.4103/0971-6203.131288
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author Nithya, L.
Raj, N. Arunai Nambi
Kumar, Arulraj
Rathinamuthu, Sasikumar
Pandey, Manish Bhushan
author_facet Nithya, L.
Raj, N. Arunai Nambi
Kumar, Arulraj
Rathinamuthu, Sasikumar
Pandey, Manish Bhushan
author_sort Nithya, L.
collection PubMed
description The aim of this study was to compare the various dosimetric parameters of dynamic multileaf collimator (MLC) intensity modulated radiation therapy (IMRT) plans with volumetric modulated arc therapy (VMAT) plans for base of tongue cases. All plans were done in Monaco planning system for Elekta synergy linear accelerator with 80 MLC. IMRT plans were planned with nine stationary beams, and VMAT plans were done for 360° arc with single arc or dual arc. The dose to the planning target volumes (PTV) for 70, 63, and 56 Gy was compared. The dose to 95, 98, and 50% volume of PTV were analyzed. The homogeneity index (HI) and the conformity index (CI) of the PTV(70) were also analyzed. IMRT and VMAT plan showed similar dose coverage, HI, and CI. Maximum dose and dose to 1-cc volume of spinal cord, planning risk volume (PRV) cord, and brain stem were compared. IMRT plan and VMAT plan showed similar results except for the 1 cc of PRV cord that received slightly higher dose in VMAT plan. Mean dose and dose to 50% volume of right and left parotid glands were analyzed. VMAT plan gave better sparing of parotid glands than IMRT. In normal tissue dose analyses VMAT was better than IMRT. The number of monitor units (MU) required for delivering the good quality of the plan and the time required to deliver the plan for IMRT and VMAT were compared. The number of MUs for VMAT was higher than that of IMRT plans. However, the delivery time was reduced by a factor of two for VMAT compared with IMRT. VMAT plans yielded good quality of the plan compared with IMRT, resulting in reduced treatment time and improved efficiency for base of tongue cases.
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spelling pubmed-40356162014-05-28 Comparative analysis of volumetric-modulated arc therapy and intensity-modulated radiotherapy for base of tongue cancer Nithya, L. Raj, N. Arunai Nambi Kumar, Arulraj Rathinamuthu, Sasikumar Pandey, Manish Bhushan J Med Phys Technical Note The aim of this study was to compare the various dosimetric parameters of dynamic multileaf collimator (MLC) intensity modulated radiation therapy (IMRT) plans with volumetric modulated arc therapy (VMAT) plans for base of tongue cases. All plans were done in Monaco planning system for Elekta synergy linear accelerator with 80 MLC. IMRT plans were planned with nine stationary beams, and VMAT plans were done for 360° arc with single arc or dual arc. The dose to the planning target volumes (PTV) for 70, 63, and 56 Gy was compared. The dose to 95, 98, and 50% volume of PTV were analyzed. The homogeneity index (HI) and the conformity index (CI) of the PTV(70) were also analyzed. IMRT and VMAT plan showed similar dose coverage, HI, and CI. Maximum dose and dose to 1-cc volume of spinal cord, planning risk volume (PRV) cord, and brain stem were compared. IMRT plan and VMAT plan showed similar results except for the 1 cc of PRV cord that received slightly higher dose in VMAT plan. Mean dose and dose to 50% volume of right and left parotid glands were analyzed. VMAT plan gave better sparing of parotid glands than IMRT. In normal tissue dose analyses VMAT was better than IMRT. The number of monitor units (MU) required for delivering the good quality of the plan and the time required to deliver the plan for IMRT and VMAT were compared. The number of MUs for VMAT was higher than that of IMRT plans. However, the delivery time was reduced by a factor of two for VMAT compared with IMRT. VMAT plans yielded good quality of the plan compared with IMRT, resulting in reduced treatment time and improved efficiency for base of tongue cases. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4035616/ /pubmed/24872611 http://dx.doi.org/10.4103/0971-6203.131288 Text en Copyright: © Journal of Medical Physics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Technical Note
Nithya, L.
Raj, N. Arunai Nambi
Kumar, Arulraj
Rathinamuthu, Sasikumar
Pandey, Manish Bhushan
Comparative analysis of volumetric-modulated arc therapy and intensity-modulated radiotherapy for base of tongue cancer
title Comparative analysis of volumetric-modulated arc therapy and intensity-modulated radiotherapy for base of tongue cancer
title_full Comparative analysis of volumetric-modulated arc therapy and intensity-modulated radiotherapy for base of tongue cancer
title_fullStr Comparative analysis of volumetric-modulated arc therapy and intensity-modulated radiotherapy for base of tongue cancer
title_full_unstemmed Comparative analysis of volumetric-modulated arc therapy and intensity-modulated radiotherapy for base of tongue cancer
title_short Comparative analysis of volumetric-modulated arc therapy and intensity-modulated radiotherapy for base of tongue cancer
title_sort comparative analysis of volumetric-modulated arc therapy and intensity-modulated radiotherapy for base of tongue cancer
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035616/
https://www.ncbi.nlm.nih.gov/pubmed/24872611
http://dx.doi.org/10.4103/0971-6203.131288
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