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The ethical dimension in published animal research in critical care: the dark side of our moon
The replacement, refinement, and reduction (3Rs) guidelines are the cornerstone of animal welfare practice for medical research. Nowadays, no animal research can be performed without being approved by an animal ethics committee. Therefore, we should expect that any published article would respect an...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035854/ https://www.ncbi.nlm.nih.gov/pubmed/24886758 http://dx.doi.org/10.1186/cc13766 |
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author | Huet, Olivier de Haan, Judy B |
author_facet | Huet, Olivier de Haan, Judy B |
author_sort | Huet, Olivier |
collection | PubMed |
description | The replacement, refinement, and reduction (3Rs) guidelines are the cornerstone of animal welfare practice for medical research. Nowadays, no animal research can be performed without being approved by an animal ethics committee. Therefore, we should expect that any published article would respect and promote the highest standard of animal welfare. However, in the previous issue of Critical Care, Bara and Joffe reported an unexpected finding: animal welfare is extremely poorly reported in critical care research publications involving animal models. This may have a significant negative impact on the reliability of the results and on future funding for our research. The ability of septic shock animal models to translate into clinical studies has been a challenge. Therefore, every means to improve the quality of these models should be pursued. Animal welfare issues should be seen as an additional benefit to achieve this goal. It is therefore critical to draw conclusions from this study to improve the standard of animal welfare in critical care research. This has already been achieved in other fields of research, and we should follow their example. |
format | Online Article Text |
id | pubmed-4035854 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-40358542015-03-13 The ethical dimension in published animal research in critical care: the dark side of our moon Huet, Olivier de Haan, Judy B Crit Care Commentary The replacement, refinement, and reduction (3Rs) guidelines are the cornerstone of animal welfare practice for medical research. Nowadays, no animal research can be performed without being approved by an animal ethics committee. Therefore, we should expect that any published article would respect and promote the highest standard of animal welfare. However, in the previous issue of Critical Care, Bara and Joffe reported an unexpected finding: animal welfare is extremely poorly reported in critical care research publications involving animal models. This may have a significant negative impact on the reliability of the results and on future funding for our research. The ability of septic shock animal models to translate into clinical studies has been a challenge. Therefore, every means to improve the quality of these models should be pursued. Animal welfare issues should be seen as an additional benefit to achieve this goal. It is therefore critical to draw conclusions from this study to improve the standard of animal welfare in critical care research. This has already been achieved in other fields of research, and we should follow their example. BioMed Central 2014 2014-03-13 /pmc/articles/PMC4035854/ /pubmed/24886758 http://dx.doi.org/10.1186/cc13766 Text en Copyright © 2014 Huet and de Haan; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 The licensee has exclusive rights to distribute this article, in any medium, for 6 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Commentary Huet, Olivier de Haan, Judy B The ethical dimension in published animal research in critical care: the dark side of our moon |
title | The ethical dimension in published animal research in critical care: the dark side of our moon |
title_full | The ethical dimension in published animal research in critical care: the dark side of our moon |
title_fullStr | The ethical dimension in published animal research in critical care: the dark side of our moon |
title_full_unstemmed | The ethical dimension in published animal research in critical care: the dark side of our moon |
title_short | The ethical dimension in published animal research in critical care: the dark side of our moon |
title_sort | ethical dimension in published animal research in critical care: the dark side of our moon |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035854/ https://www.ncbi.nlm.nih.gov/pubmed/24886758 http://dx.doi.org/10.1186/cc13766 |
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