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The polyene antifungals, amphotericin B and nystatin, cause cell death in Saccharomyces cerevisiae by a distinct mechanism to amphibian-derived antimicrobial peptides

BACKGROUND: There is a pressing need to identify novel antifungal drug targets to aid in the therapy of life-threatening mycoses and overcome increasing drug resistance. Identifying specific mechanisms of action of membrane-interacting antimicrobial drugs on the model fungus Saccharomyces cerevisiae...

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Detalles Bibliográficos
Autores principales:	Serhan, George, Stack, Colin M, Perrone, Gabriel G, Morton, Charles Oliver
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036090/ https://www.ncbi.nlm.nih.gov/pubmed/24884795 http://dx.doi.org/10.1186/1476-0711-13-18

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