Progressive Outer Retinal Necrosis and Immunosuppressive Therapy in Myasthenia Gravis

INTRODUCTION: Progressive outer retinal necrosis (PORN) is a rare but devastating infectious retinitis associated with varicella zoster virus (VZV) and responsible for severe visual loss. CASE REPORT: A 59-year-old man treated for generalized myasthenia with oral azathioprine and prednisone presente...

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Autores principales: Coisy, Solène, Ebran, Jean-Marc, Milea, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Published online: April, 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036147/
https://www.ncbi.nlm.nih.gov/pubmed/24926266
http://dx.doi.org/10.1159/000362662
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author Coisy, Solène
Ebran, Jean-Marc
Milea, Dan
author_facet Coisy, Solène
Ebran, Jean-Marc
Milea, Dan
author_sort Coisy, Solène
collection PubMed
description INTRODUCTION: Progressive outer retinal necrosis (PORN) is a rare but devastating infectious retinitis associated with varicella zoster virus (VZV) and responsible for severe visual loss. CASE REPORT: A 59-year-old man treated for generalized myasthenia with oral azathioprine and prednisone presented with severe unilateral necrotizing retinitis. Polymerase chain reaction of the aqueous and vitreous humors was diagnostic for VZV PORN. CONCLUSION: VZV PORN is a severe potential ocular complication of immunosuppression, prompting urgent diagnosis and appropriate treatment.
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spelling pubmed-40361472014-06-12 Progressive Outer Retinal Necrosis and Immunosuppressive Therapy in Myasthenia Gravis Coisy, Solène Ebran, Jean-Marc Milea, Dan Case Rep Ophthalmol Published online: April, 2014 INTRODUCTION: Progressive outer retinal necrosis (PORN) is a rare but devastating infectious retinitis associated with varicella zoster virus (VZV) and responsible for severe visual loss. CASE REPORT: A 59-year-old man treated for generalized myasthenia with oral azathioprine and prednisone presented with severe unilateral necrotizing retinitis. Polymerase chain reaction of the aqueous and vitreous humors was diagnostic for VZV PORN. CONCLUSION: VZV PORN is a severe potential ocular complication of immunosuppression, prompting urgent diagnosis and appropriate treatment. S. Karger AG 2014-04-22 /pmc/articles/PMC4036147/ /pubmed/24926266 http://dx.doi.org/10.1159/000362662 Text en Copyright © 2014 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: April, 2014
Coisy, Solène
Ebran, Jean-Marc
Milea, Dan
Progressive Outer Retinal Necrosis and Immunosuppressive Therapy in Myasthenia Gravis
title Progressive Outer Retinal Necrosis and Immunosuppressive Therapy in Myasthenia Gravis
title_full Progressive Outer Retinal Necrosis and Immunosuppressive Therapy in Myasthenia Gravis
title_fullStr Progressive Outer Retinal Necrosis and Immunosuppressive Therapy in Myasthenia Gravis
title_full_unstemmed Progressive Outer Retinal Necrosis and Immunosuppressive Therapy in Myasthenia Gravis
title_short Progressive Outer Retinal Necrosis and Immunosuppressive Therapy in Myasthenia Gravis
title_sort progressive outer retinal necrosis and immunosuppressive therapy in myasthenia gravis
topic Published online: April, 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036147/
https://www.ncbi.nlm.nih.gov/pubmed/24926266
http://dx.doi.org/10.1159/000362662
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