CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment

Chemokines are crucial autocrine and paracrine players in tumor development. In particular, CXCL12, through its receptors CXCR4 and CXCR7, affects tumor progression by controlling cancer cell survival, proliferation and migration, and, indirectly, via angiogenesis or recruiting immune cells. Gliobla...

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Detalles Bibliográficos
Autores principales: Würth, Roberto, Bajetto, Adriana, Harrison, Jeffrey K., Barbieri, Federica, Florio, Tullio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036438/
https://www.ncbi.nlm.nih.gov/pubmed/24904289
http://dx.doi.org/10.3389/fncel.2014.00144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036438/
https://www.ncbi.nlm.nih.gov/pubmed/24904289
http://dx.doi.org/10.3389/fncel.2014.00144

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