Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease

Effective treatment options for advanced colorectal cancer (CRC) are limited, survival rates are poor and this disease continues to be a leading cause of cancer-related deaths worldwide. Despite being a highly heterogeneous disease, a large subset of individuals with sporadic CRC typically harbor re...

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Detalles Bibliográficos
Autores principales: Belmont, Peter J., Budinska, Eva, Jiang, Ping, Sinnamon, Mark J., Coffee, Erin, Roper, Jatin, Xie, Tao, Rejto, Paul A., Derkits, Sahra, Sansom, Owen J., Delorenzi, Mauro, Tejpar, Sabine, Hung, Kenneth E., Martin, Eric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036469/
https://www.ncbi.nlm.nih.gov/pubmed/24742783
http://dx.doi.org/10.1242/dmm.013904

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