Oncolytic Virotherapy of Canine and Feline Cancer

Cancer is the leading cause of disease-related death in companion animals such as dogs and cats. Despite recent progress in the diagnosis and treatment of advanced canine and feline cancer, overall patient treatment outcome has not been substantially improved. Virotherapy using oncolytic viruses is...

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Autores principales: Gentschev, Ivaylo, Patil, Sandeep S., Petrov, Ivan, Cappello, Joseph, Adelfinger, Marion, Szalay, Aladar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036544/
https://www.ncbi.nlm.nih.gov/pubmed/24841386
http://dx.doi.org/10.3390/v6052122
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author Gentschev, Ivaylo
Patil, Sandeep S.
Petrov, Ivan
Cappello, Joseph
Adelfinger, Marion
Szalay, Aladar A.
author_facet Gentschev, Ivaylo
Patil, Sandeep S.
Petrov, Ivan
Cappello, Joseph
Adelfinger, Marion
Szalay, Aladar A.
author_sort Gentschev, Ivaylo
collection PubMed
description Cancer is the leading cause of disease-related death in companion animals such as dogs and cats. Despite recent progress in the diagnosis and treatment of advanced canine and feline cancer, overall patient treatment outcome has not been substantially improved. Virotherapy using oncolytic viruses is one promising new strategy for cancer therapy. Oncolytic viruses (OVs) preferentially infect and lyse cancer cells, without causing excessive damage to surrounding healthy tissue, and initiate tumor-specific immunity. The current review describes the use of different oncolytic viruses for cancer therapy and their application to canine and feline cancer.
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spelling pubmed-40365442014-05-28 Oncolytic Virotherapy of Canine and Feline Cancer Gentschev, Ivaylo Patil, Sandeep S. Petrov, Ivan Cappello, Joseph Adelfinger, Marion Szalay, Aladar A. Viruses Review Cancer is the leading cause of disease-related death in companion animals such as dogs and cats. Despite recent progress in the diagnosis and treatment of advanced canine and feline cancer, overall patient treatment outcome has not been substantially improved. Virotherapy using oncolytic viruses is one promising new strategy for cancer therapy. Oncolytic viruses (OVs) preferentially infect and lyse cancer cells, without causing excessive damage to surrounding healthy tissue, and initiate tumor-specific immunity. The current review describes the use of different oncolytic viruses for cancer therapy and their application to canine and feline cancer. MDPI 2014-05-16 /pmc/articles/PMC4036544/ /pubmed/24841386 http://dx.doi.org/10.3390/v6052122 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Gentschev, Ivaylo
Patil, Sandeep S.
Petrov, Ivan
Cappello, Joseph
Adelfinger, Marion
Szalay, Aladar A.
Oncolytic Virotherapy of Canine and Feline Cancer
title Oncolytic Virotherapy of Canine and Feline Cancer
title_full Oncolytic Virotherapy of Canine and Feline Cancer
title_fullStr Oncolytic Virotherapy of Canine and Feline Cancer
title_full_unstemmed Oncolytic Virotherapy of Canine and Feline Cancer
title_short Oncolytic Virotherapy of Canine and Feline Cancer
title_sort oncolytic virotherapy of canine and feline cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036544/
https://www.ncbi.nlm.nih.gov/pubmed/24841386
http://dx.doi.org/10.3390/v6052122
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