Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks

While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general "black box" warning for cardiovascular adverse events for NSAIDs. This review explores the differe...

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Detalles Bibliográficos
Autores principales: Meek, Inger L., van de Laar, Mart A.F.J., Vonkeman, Harald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036661/
https://www.ncbi.nlm.nih.gov/pubmed/27713346
http://dx.doi.org/10.3390/ph3072146
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author Meek, Inger L.
van de Laar, Mart A.F.J.
Vonkeman, Harald E.
author_facet Meek, Inger L.
van de Laar, Mart A.F.J.
Vonkeman, Harald E.
author_sort Meek, Inger L.
collection PubMed
description While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general "black box" warning for cardiovascular adverse events for NSAIDs. This review explores the different mechanisms underlying the protective effects of aspirin, the NSAID associated renovascular effects causing hypertension, edema and heart failure, the cardiovascular effects causing myocardial infarction and stroke, and the possible deleterious interaction between NSAIDs and aspirin.
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spelling pubmed-40366612014-05-28 Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks Meek, Inger L. van de Laar, Mart A.F.J. Vonkeman, Harald E. Pharmaceuticals (Basel) Review While aspirin may offer protection, other non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) can cause serious cardiovascular side effects and complications. This has led to a general "black box" warning for cardiovascular adverse events for NSAIDs. This review explores the different mechanisms underlying the protective effects of aspirin, the NSAID associated renovascular effects causing hypertension, edema and heart failure, the cardiovascular effects causing myocardial infarction and stroke, and the possible deleterious interaction between NSAIDs and aspirin. MDPI 2010-07-07 /pmc/articles/PMC4036661/ /pubmed/27713346 http://dx.doi.org/10.3390/ph3072146 Text en © 2010 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an Open Access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Meek, Inger L.
van de Laar, Mart A.F.J.
Vonkeman, Harald E.
Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks
title Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks
title_full Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks
title_fullStr Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks
title_full_unstemmed Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks
title_short Non-Steroidal Anti-Inflammatory Drugs: An Overview of Cardiovascular Risks
title_sort non-steroidal anti-inflammatory drugs: an overview of cardiovascular risks
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036661/
https://www.ncbi.nlm.nih.gov/pubmed/27713346
http://dx.doi.org/10.3390/ph3072146
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