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Glutaric Acid-Mediated Apoptosis in Primary Striatal Neurons

Glutaric acid (GA) has been implicated in the mechanism of neurodegeneration in glutaric aciduria type I. In the present study, the potential cytotoxic effects of GA (0.1~50 mM for 24~96 h) were examined in cultured primary rat striatal neurons. Results showed increase in the number of cells labeled...

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Detalles Bibliográficos
Autores principales:	Tian, Fengyan, Fu, Xi, Gao, Jinzhi, Ying, Yanqin, Hou, Ling, Liang, Yan, Ning, Qin, Luo, Xiaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036723/ https://www.ncbi.nlm.nih.gov/pubmed/24900967 http://dx.doi.org/10.1155/2014/484731

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