Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes

We investigated sequential episodes of acute norovirus gastroenteritis in a young child within an 11-month period. The infections were caused by 2 distinct genotypes (GII.4 and GII.6). Failure to achieve cross-protective immunity was linked to absence of an enduring and cross-reactive mucosal immune...

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Detalles Bibliográficos
Autores principales: Parra, Gabriel I., Green, Kim Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2014
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036768/
https://www.ncbi.nlm.nih.gov/pubmed/24857806
http://dx.doi.org/10.3201/eid2006.131627
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author Parra, Gabriel I.
Green, Kim Y.
author_facet Parra, Gabriel I.
Green, Kim Y.
author_sort Parra, Gabriel I.
collection PubMed
description We investigated sequential episodes of acute norovirus gastroenteritis in a young child within an 11-month period. The infections were caused by 2 distinct genotypes (GII.4 and GII.6). Failure to achieve cross-protective immunity was linked to absence of an enduring and cross-reactive mucosal immune response, a critical consideration for vaccine design.
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spelling pubmed-40367682014-06-04 Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes Parra, Gabriel I. Green, Kim Y. Emerg Infect Dis Dispatch We investigated sequential episodes of acute norovirus gastroenteritis in a young child within an 11-month period. The infections were caused by 2 distinct genotypes (GII.4 and GII.6). Failure to achieve cross-protective immunity was linked to absence of an enduring and cross-reactive mucosal immune response, a critical consideration for vaccine design. Centers for Disease Control and Prevention 2014-06 /pmc/articles/PMC4036768/ /pubmed/24857806 http://dx.doi.org/10.3201/eid2006.131627 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Parra, Gabriel I.
Green, Kim Y.
Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_full Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_fullStr Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_full_unstemmed Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_short Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_sort sequential gastroenteritis episodes caused by 2 norovirus genotypes
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036768/
https://www.ncbi.nlm.nih.gov/pubmed/24857806
http://dx.doi.org/10.3201/eid2006.131627
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