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HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells

BACKGROUND: We have shown that HIV-1 Tat interaction with MAP2K3, MAP2K6, and IRF7 promoters is key to IFN-stimulated genes (ISG) activation in immature dendritic cells and macrophages. RESULTS: We evaluated how Tat alleles and mutants differ in cellular gene modulation of immature dendritic cells a...

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Detalles Bibliográficos
Autores principales:	Kukkonen, Sami, Martinez-Viedma, Maria Del Pilar, Kim, Nayoung, Manrique, Mariana, Aldovini, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036831/ https://www.ncbi.nlm.nih.gov/pubmed/24742347 http://dx.doi.org/10.1186/1742-4690-11-30

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