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Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study

Background. The objective of this study was to assess the association of glycemic status and decreased renal function as determined by estimated glomerular filtration rate (eGFR) and albuminuria in an adult Taiwanese metropolitan population. Methods. We did a cross-sectional survey in a representati...

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Autores principales: Lin, Cheng-Chieh, Li, Chia-Ing, Liu, Chiu-Shong, Lin, Wen-Yuan, Lin, Chih-Hsueh, Lai, Ming-May, Lee, Yih-Dar, Chen, Ching-Chu, Yang, Chuan-Wei, Li, Tsai-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037121/
https://www.ncbi.nlm.nih.gov/pubmed/24900991
http://dx.doi.org/10.1155/2014/841497
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author Lin, Cheng-Chieh
Li, Chia-Ing
Liu, Chiu-Shong
Lin, Wen-Yuan
Lin, Chih-Hsueh
Lai, Ming-May
Lee, Yih-Dar
Chen, Ching-Chu
Yang, Chuan-Wei
Li, Tsai-Chung
author_facet Lin, Cheng-Chieh
Li, Chia-Ing
Liu, Chiu-Shong
Lin, Wen-Yuan
Lin, Chih-Hsueh
Lai, Ming-May
Lee, Yih-Dar
Chen, Ching-Chu
Yang, Chuan-Wei
Li, Tsai-Chung
author_sort Lin, Cheng-Chieh
collection PubMed
description Background. The objective of this study was to assess the association of glycemic status and decreased renal function as determined by estimated glomerular filtration rate (eGFR) and albuminuria in an adult Taiwanese metropolitan population. Methods. We did a cross-sectional survey in a representative sample of 2,350 Taiwanese adults aged 40 years and over living in a metropolitan city in Taiwan from 2004 to 2005. Glycemic status was classified as normal glycemia, hyperglycemia, and type 2 diabetes (T2D). Renal function was assessed with eGFR using modified Modification of Diet in Renal Disease Study equation for Chinese. Albuminuria was determined by the urinary albumin-creatinine ratio. Decreased renal function was defined as eGFR <60 mL/min/1.73 m(2) and albuminuria as the albumin-creatinine ratio >30 mg g(−1) creatinine. Results. 593 (25.23%) had hyperglycemia and 287 (12.21%) had T2D. As glycemia level increased, the prevalence of albuminuria and decreased eGFR increased. After adjustment, T2D was associated with an OR of 2.93 (95% CI: 2.11–4.07) for albuminuria, and an OR of 2.05 (95% CI: 1.18–3.58) for decreased eGFR. Conclusions. In a representative sample from a metropolitan city in Taiwan, T2D was associated with albuminuria and decreased eGFR.
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spelling pubmed-40371212014-06-04 Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study Lin, Cheng-Chieh Li, Chia-Ing Liu, Chiu-Shong Lin, Wen-Yuan Lin, Chih-Hsueh Lai, Ming-May Lee, Yih-Dar Chen, Ching-Chu Yang, Chuan-Wei Li, Tsai-Chung Biomed Res Int Research Article Background. The objective of this study was to assess the association of glycemic status and decreased renal function as determined by estimated glomerular filtration rate (eGFR) and albuminuria in an adult Taiwanese metropolitan population. Methods. We did a cross-sectional survey in a representative sample of 2,350 Taiwanese adults aged 40 years and over living in a metropolitan city in Taiwan from 2004 to 2005. Glycemic status was classified as normal glycemia, hyperglycemia, and type 2 diabetes (T2D). Renal function was assessed with eGFR using modified Modification of Diet in Renal Disease Study equation for Chinese. Albuminuria was determined by the urinary albumin-creatinine ratio. Decreased renal function was defined as eGFR <60 mL/min/1.73 m(2) and albuminuria as the albumin-creatinine ratio >30 mg g(−1) creatinine. Results. 593 (25.23%) had hyperglycemia and 287 (12.21%) had T2D. As glycemia level increased, the prevalence of albuminuria and decreased eGFR increased. After adjustment, T2D was associated with an OR of 2.93 (95% CI: 2.11–4.07) for albuminuria, and an OR of 2.05 (95% CI: 1.18–3.58) for decreased eGFR. Conclusions. In a representative sample from a metropolitan city in Taiwan, T2D was associated with albuminuria and decreased eGFR. Hindawi Publishing Corporation 2014 2014-05-12 /pmc/articles/PMC4037121/ /pubmed/24900991 http://dx.doi.org/10.1155/2014/841497 Text en Copyright © 2014 Cheng-Chieh Lin et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Lin, Cheng-Chieh
Li, Chia-Ing
Liu, Chiu-Shong
Lin, Wen-Yuan
Lin, Chih-Hsueh
Lai, Ming-May
Lee, Yih-Dar
Chen, Ching-Chu
Yang, Chuan-Wei
Li, Tsai-Chung
Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study
title Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study
title_full Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study
title_fullStr Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study
title_full_unstemmed Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study
title_short Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study
title_sort risks of decreased renal function and increased albuminuria for glycemic status and metabolic syndrome components: taichung community health study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037121/
https://www.ncbi.nlm.nih.gov/pubmed/24900991
http://dx.doi.org/10.1155/2014/841497
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