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Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study
Background. The objective of this study was to assess the association of glycemic status and decreased renal function as determined by estimated glomerular filtration rate (eGFR) and albuminuria in an adult Taiwanese metropolitan population. Methods. We did a cross-sectional survey in a representati...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037121/ https://www.ncbi.nlm.nih.gov/pubmed/24900991 http://dx.doi.org/10.1155/2014/841497 |
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author | Lin, Cheng-Chieh Li, Chia-Ing Liu, Chiu-Shong Lin, Wen-Yuan Lin, Chih-Hsueh Lai, Ming-May Lee, Yih-Dar Chen, Ching-Chu Yang, Chuan-Wei Li, Tsai-Chung |
author_facet | Lin, Cheng-Chieh Li, Chia-Ing Liu, Chiu-Shong Lin, Wen-Yuan Lin, Chih-Hsueh Lai, Ming-May Lee, Yih-Dar Chen, Ching-Chu Yang, Chuan-Wei Li, Tsai-Chung |
author_sort | Lin, Cheng-Chieh |
collection | PubMed |
description | Background. The objective of this study was to assess the association of glycemic status and decreased renal function as determined by estimated glomerular filtration rate (eGFR) and albuminuria in an adult Taiwanese metropolitan population. Methods. We did a cross-sectional survey in a representative sample of 2,350 Taiwanese adults aged 40 years and over living in a metropolitan city in Taiwan from 2004 to 2005. Glycemic status was classified as normal glycemia, hyperglycemia, and type 2 diabetes (T2D). Renal function was assessed with eGFR using modified Modification of Diet in Renal Disease Study equation for Chinese. Albuminuria was determined by the urinary albumin-creatinine ratio. Decreased renal function was defined as eGFR <60 mL/min/1.73 m(2) and albuminuria as the albumin-creatinine ratio >30 mg g(−1) creatinine. Results. 593 (25.23%) had hyperglycemia and 287 (12.21%) had T2D. As glycemia level increased, the prevalence of albuminuria and decreased eGFR increased. After adjustment, T2D was associated with an OR of 2.93 (95% CI: 2.11–4.07) for albuminuria, and an OR of 2.05 (95% CI: 1.18–3.58) for decreased eGFR. Conclusions. In a representative sample from a metropolitan city in Taiwan, T2D was associated with albuminuria and decreased eGFR. |
format | Online Article Text |
id | pubmed-4037121 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-40371212014-06-04 Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study Lin, Cheng-Chieh Li, Chia-Ing Liu, Chiu-Shong Lin, Wen-Yuan Lin, Chih-Hsueh Lai, Ming-May Lee, Yih-Dar Chen, Ching-Chu Yang, Chuan-Wei Li, Tsai-Chung Biomed Res Int Research Article Background. The objective of this study was to assess the association of glycemic status and decreased renal function as determined by estimated glomerular filtration rate (eGFR) and albuminuria in an adult Taiwanese metropolitan population. Methods. We did a cross-sectional survey in a representative sample of 2,350 Taiwanese adults aged 40 years and over living in a metropolitan city in Taiwan from 2004 to 2005. Glycemic status was classified as normal glycemia, hyperglycemia, and type 2 diabetes (T2D). Renal function was assessed with eGFR using modified Modification of Diet in Renal Disease Study equation for Chinese. Albuminuria was determined by the urinary albumin-creatinine ratio. Decreased renal function was defined as eGFR <60 mL/min/1.73 m(2) and albuminuria as the albumin-creatinine ratio >30 mg g(−1) creatinine. Results. 593 (25.23%) had hyperglycemia and 287 (12.21%) had T2D. As glycemia level increased, the prevalence of albuminuria and decreased eGFR increased. After adjustment, T2D was associated with an OR of 2.93 (95% CI: 2.11–4.07) for albuminuria, and an OR of 2.05 (95% CI: 1.18–3.58) for decreased eGFR. Conclusions. In a representative sample from a metropolitan city in Taiwan, T2D was associated with albuminuria and decreased eGFR. Hindawi Publishing Corporation 2014 2014-05-12 /pmc/articles/PMC4037121/ /pubmed/24900991 http://dx.doi.org/10.1155/2014/841497 Text en Copyright © 2014 Cheng-Chieh Lin et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Lin, Cheng-Chieh Li, Chia-Ing Liu, Chiu-Shong Lin, Wen-Yuan Lin, Chih-Hsueh Lai, Ming-May Lee, Yih-Dar Chen, Ching-Chu Yang, Chuan-Wei Li, Tsai-Chung Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study |
title | Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study |
title_full | Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study |
title_fullStr | Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study |
title_full_unstemmed | Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study |
title_short | Risks of Decreased Renal Function and Increased Albuminuria for Glycemic Status and Metabolic Syndrome Components: Taichung Community Health Study |
title_sort | risks of decreased renal function and increased albuminuria for glycemic status and metabolic syndrome components: taichung community health study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037121/ https://www.ncbi.nlm.nih.gov/pubmed/24900991 http://dx.doi.org/10.1155/2014/841497 |
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