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A Novel Formulation of Tigecycline Has Enhanced Stability and Sustained Antibacterial and Antileukemic Activity
Tigecycline is a broad-spectrum, first-in-class glycylcycline antibiotic currently used to treat complicated skin and intra-abdominal infections, as well as community-acquired pneumonia. In addition, we have demonstrated that tigecycline also has in vitro and in vivo activity against acute myeloid l...
Autores principales: | Jitkova, Yulia, Gronda, Marcela, Hurren, Rose, Wang, Xiaoming, Goard, Carolyn A., Jhas, Bozhena, Schimmer, Aaron D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037176/ https://www.ncbi.nlm.nih.gov/pubmed/24871339 http://dx.doi.org/10.1371/journal.pone.0095281 |
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