Investigating the Relation between Stochastic Differentiation, Homeostasis and Clonal Expansion in Intestinal Crypts via Multiscale Modeling

Colorectal tumors originate and develop within intestinal crypts. Even though some of the essential phenomena that characterize crypt structure and dynamics have been effectively described in the past, the relation between the differentiation process and the overall crypt homeostasis is still only p...

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Detalles Bibliográficos
Autores principales: Graudenzi, Alex, Caravagna, Giulio, De Matteis, Giovanni, Antoniotti, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037186/
https://www.ncbi.nlm.nih.gov/pubmed/24869488
http://dx.doi.org/10.1371/journal.pone.0097272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037186/
https://www.ncbi.nlm.nih.gov/pubmed/24869488
http://dx.doi.org/10.1371/journal.pone.0097272

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